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FDA Public Workshop: Assessment of Cardiovascular Toxicities in Immuno-oncology Trials
Posted by Moslehi on January 22, 2018

On Friday, December 1, 2017, the U.S. Food & Drug Administration (FDA) announced a public workshop entitled, “Assessment of Cardiovascular Toxicities in Immuno-oncology Trials”. This workshop provided a forum for discussion of cardiovascular toxicities in immuno-oncology clinical trials. The workshop focused on the identification...

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Manuscripts published in Circulation raise awareness for immune checkpoint inhibitor associated myocarditis
Posted by Moslehi on January 22, 2018

Two manuscripts published on November 21, 2017 of the journal Circulation bring additional awareness for the syndrome of immune checkpoint-inhibitor (ICI)-associated myocarditis. Thuny and colleagues (Hospital Nord, Marseille, France) present a case series of 30 patients with ICI-induced cardiotoxicity. Cardiotoxicity was diagnosed at a...

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Cardio-Oncology highlighted at American Heart Association Annual Meeting 2017
Posted by Moslehi on January 22, 2018

There were several cardio-oncology sessions at the American Heart Association (AHA) annual meeting which occurred in November 2017 in Anaheim, California. A session called “The Emerging Science of Cardio-Oncology” focused on the rapidly evolving area of clinical practice in cancer patients with heart failure or acute coronary...

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Terrific @nih_nhlbi meeting chaired by @DrCihakovaD & Les Cooper on #Myocarditis #CardioImmunology! Energized by the community of investigators! Clearly need 2 understand mechanisms better before we can help patients BUT many new tools in #immunology to use & which can teach us!

@KAmancherla in partnership w/ @JuanQinMed shows that GCM has a distinct transcriptomic profile compared to other forms of myocarditis and utilizes an integration of RNASeq-Drug gene interaction to identify novel Rx targets for GCM. Thanks to all of our mentors & collaborators!

Proud of Vandy cardiology fellow @KAmancherla in A+ work providing new insights into pathogenesis of Giant Cell Myocarditis. Kaushik (a former Osler marine, though slightly weaker firm - Thayer)'s work builds on previous Hopkins legends - the late KLB & @MKIttlesonMD @DukeHFDoc

Great work for @American_Heart #CardioOnc subcommittee member & FIT @Melissa_Moey at @EastCarolina working with @DrJESalem @unico_greco on CV tox associated w/ prostate cancer therapies beyond ADT. @PCFnews @AHA_Research @AHAScience @PCF_Science